Acute tumor lysis syndrome associated with concurrent biochemotherapy of metastatic melanoma
نویسندگان
چکیده
منابع مشابه
Spontaneous Tumor Lysis Syndrome in Metastatic Melanoma
Tumor lysis syndrome (TLS) complicating non-hematologic malignancy is infrequent and spontaneous TLS is a very rare occurrence in patients with solid tumors. We report a case of spontaneous TLS in a patient with metastatic melanoma. Clinicians should have awareness of the possibility of spontaneous TLS in patients with solid tumors and should recognize the clinical presentation and laboratory t...
متن کاملTumour lysis syndrome in a patient with metastatic melanoma treated with biochemotherapy.
Sir, Tumour lysis syndrome (TLS) may complicate the treatment of highly proliferative, chemosensitive haematological malignancies w1x. Rapid cell death is associated with hyperuricaemia, hypocalcaemia, hyperphosphataemia, and hyperkalaemia w2x. Acute hyperuricaemic nephropathy (AHN) arises from precipitation of uric acid crystals within renal tubules and subsequent uptake into tubular epithelia...
متن کاملMetastatic melanoma: chemotherapy to biochemotherapy.
BACKGROUND Single-agent or combination chemotherapy regimens have not impacted the short median survival of patients with metastatic melanoma, and complete or durable responses are rare. Biologic response modifiers (interferon and interleukin-2) have produced durable remissions in a small cohort of patients, and phase II trials of biochemotherapy suggest more benefit. METHODS The authors retr...
متن کاملIdentification of children with acute lymphoblastic leukemia at low risk for tumor lysis syndrome
Background and Objective: Tumor lysis syndrome (TLS) could occur before, during or after the initiation of chemotherapy in patients with cancers especially those with hematologic malignancies. This study was designed to determine the prevalence and predictors of TLS in children with Acute Lymphoblastic Lymphoma (ALL) and to develop a sensitive prediction rule to identify patients at low risk of...
متن کاملAcute Respiratory Distress Syndrome Associated with Tumor Lysis Syndrome in a Child with Acute Lymphoblastic Leukemia
Tumor lysis syndrome is a serious and dangerous complication usually associated with antiblastic treatment in some malignancies characterized by high cell turn-over. Mild or severe electrolyte abnormalities including high serum levels of uric acid, potassium, phosphorus, creatinine, bun and reduction of calcium can be responsible for multi-organ failure, involving mostly kidneys, heart and cent...
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ژورنال
عنوان ژورنال: Cancer
سال: 1999
ISSN: 0008-543X,1097-0142
DOI: 10.1002/(sici)1097-0142(19990301)85:5<1055::aid-cncr7>3.0.co;2-3